Mild SLE Usually Means Healthy Pregnancies

Major Finding: In all, 81% of the women with low-activity disease had a favorable outcome. Indicated preterm delivery or small for gestational age occurred in 9.1% of SLE pregnancies. In addition, 10% of the mothers developed preeclampsia; the national level is closer to 4%.

Data Source: A study of 333 pregnancies in women with low-activity systemic lupus erythematosus as part of the PROMISSE (Predictors of Pregnancy Outcome: Biomarkers in Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus) study.

Disclosures: The study was funded by a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Dr. Buyon reported that she has no relevant financial disclosures.